Search results for "Endoscopic imaging"
showing 6 items of 6 documents
Advanced endoscopic imaging for gastric cancer assessment: new insights with new optics?
2014
The most immediate strategy for improving survival of gastric cancer patients is secondary prevention through diagnosis of early gastric cancer either through screening or follow-up of individuals at high risk. Endoscopy examination is therefore of paramount importance and two general steps are to be known in assessing gastric mucosa - detection and characterization. Over the past decade, the advent of advanced endoscopic imaging technology led to diverse descriptions of these modalities reporting them to be useful in this setting. In this review, we aim at summarizing the current evidence on the use of advance imaging in individuals at high-risk (i.e., advance stages of gastric atrophy/int…
ADVANCED ENDOSCOPIC IMAGING FOR SURVEILLANCE FOR DYSPLASIA AND COLORECTAL CANCER IN INFLAMMATORY BOWEL DISEASE: COULD THE PATHOLOGIST BE FURTHER HELP…
2014
Patients with inflammatory bowel disease (IBD) have an increased risk of developing intestinal cancer. The magnitude of that increased risk as well as how best to mitigate it remain a topic of ongoing investigation in the field. It is important to quantify the risk of colorectal cancer in association with IBD. The reported risk varies widely between studies. This is partly due to the different methodologies used in the studies. Because of the limitations of surveillance strategies based on the detection of dysplasia, advanced endoscopic imaging and techniques involving the detection of alterations in mucosal antigens and genetic abnormalities are being investigated. Development of new bioma…
Confocal Laser Endomicroscopy: Technical Advances and Clinical Applications
2010
Since its introduction in 2004, confocal laser endomicroscopy (CLE) has emerged as a valuable tool for gastrointestinal endoscopic imaging. Endomicroscopy enables the endoscopist to obtain real time in vivo histology during ongoing endoscopy thereby creating “optical biopsies.” To date, numerous studies have shown potential applications of endomicroscopy in the clinical setting, including in vivo diagnosis of esophageal squamous cell carcinoma, Barrett’s esophagus, celiac disease, and colonic polyps. Moreover, recent data suggest the potential application of endomicroscopy in the field of molecular imaging. Additionally, in recent months new applications and developments in the field of con…
Molecular endoscopic imaging: the future is bright
2019
The prediction and final survival rate of gastrointestinal cancers are dependent on the stage of disease. The ideal would be to detect those gastrointestinal lesions at early stage or even premalignant forms which are difficult to detect by conventional endoscopy with white light optical imaging as they show minimum or no changes in morphological characteristics and are thus left untreated. The introduction of molecular imaging has greatly changed the pattern for detecting gastrointestinal lesions from purely macroscopic structural imaging to the molecular level. It allows microscopic examination of the gastrointestinal mucosa with endoscopy after the topical or systemic application of mol…
Advanced Endoscopic Imaging Methods
2021
Endoscopic imaging is the mainstay of gastrointestinal endoscopy and has experienced remarkable improvements in recent decades. Further endoscopic innovations stemming from major technological advances such as artificial intelligence and deep learning are at advanced stages of development and will be increasingly deployed in routine clinical practice. These will improve the detection and enable real-time optical diagnosis of pathologies in the gastrointestinal tract. Furthermore, the utilization of endoscopic robots may result in higher diagnostic yield and greater patient comfort. This chapter covers the most recent developments around computer-assisted diagnosis, hypoxia and three-dimensi…
Enhanced Endoscopy in Inflammatory Bowel Disease
2011
Enhanced imaging technologies are of special importance in patients with inflammatory bowel diseases. Patients with long-lasting colitis face an increased cancer risk and neoplastic changes often evolve as subtle, multifocal, and flat lesions. Enhanced endoscopic imaging technologies enable better visualization of the mucosal architecture. These new available information can be used to better detect and characterize colorectal lesions. The better endoscopic judgment leads to more targeted biopsies and cancer detection can be facilitated. This new concept of “smart biopsies” is in particular important for screening purposes. Furthermore, the technique of endomicroscopy enables in vivo histol…